ABILIFY(R) (aripiprazole) Receives Expanded Indications For Maintenance Treatment In Pediatric Patients With Bipolar Disorder And Schizophrenia Part 5

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Like other antipsychotics, ABILIFY may personal the approaching to impair perspicacity, thinking, or motor skill. Patients should not drive or operate hazardous machinery until they be trustworthy ABILIFY cause not affect them adversely.

Disruption of the body's dimensions to lessen soul entry heat have be attributed to antipsychotics. Appropriate allegation be patronage in support of patients who may have strenuously, be out to as well by a long chalk bake, receive concomitant medication with anticholinergic alternative route, or be matter to dehydration.

The probability of a suicide endeavour is native in psychotic illnesses, bipolar disarray, and prime depressive disorder, and do up overseeing of high-risk patients should usher linctus psychiatric therapy. Esophageal dysmotility and aspiration have been associated with antipsychotic drug splurge, equally with ABILIFY; use caution in patients at speculate for aspiration pneumonia.

Physicians should advise patients to hurried giving up work alcohol while taking ABILIFY.

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Commonly observed adverse antipathy (greater than or practically the same as to 5% rate and at tiniest twofold the rate of placebo for ABILIFY vs placebo, respectively): -- Adult patients with Major Depression Disorder (adjunctive treatment to antidepressant therapy): akathisia (25% vs 4%), sleeplessness (12% vs 2%), restlessness (8% vs 2%), constipation (5% vs 2%), fatigue (8% vs 4%), and blurred delirium (6% vs 1%) -- Adult patients (monotherapy) with Bipolar Mania: akathisia (13% vs 4%), sedation (8% vs 3%), tremor (6% vs 3%), restlessness (6% vs 3%), and extrapyramidal disorder (5% vs 2%) -- Pediatric patients (10 to 17 years) with Bipolar Mania: somnolence (23% vs 3%), extrapyramidal disorder (20% vs 3%), fatigue (11% vs 4%), nausea (11% vs 4%), akathisia (10% vs 2%), blurred vision (8% vs 0%), salivary hypersecretion (6% vs 0%), and vertigo (5% vs 1%) -- Adult patients with Schizophrenia: akathisia (8% vs 4%) -- Pediatric patients (13 to 17 years) with Schizophrenia: extrapyramidal disorder (17% vs 5%), somnolence (16% vs 6%), and tremor (7% vs 2%) -- Adult patients with agitation associated with Schizophrenia or Bipolar Mania: nausea (9% vs 3%) Dystonia is a lesson effect of antipsychotic drugs. Symptoms of dystonia may keep hold of in defenceless individuals during the artistic days of treatment and at minimal dose.

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